abstract：:Background: Hypomanic episodes are characterized by increased goal-directed behavior and psychomotor agitation. While the affective, cognitive, and behavioral manifestations of such episodes are well-documented, their physiological influence on aerobic capacity and cardiopulmonary functioning are unknown. Methods: We ...

journal_title：Frontiers in psychiatry

authors： Shoval A,Armstrong HF,Vakhrusheva J,Ballon JS,Bartels MN,Kimhy D

更新日期：2018-12-21 00:00:00

abstract：:Background: A large portion of previous studies that have demonstrated brain gray matter reduction in individuals who use methamphetamine (MA) have focused on short-term abstinence, but few studies have focused on the effects of long-term abstinence of methamphetamine on brain structures. Materials and Methods: Our st...

journal_title：Frontiers in psychiatry

authors： Zhang Z,He L,Huang S,Fan L,Li Y,Li P,Zhang J,Liu J,Yang R

更新日期：2018-12-20 00:00:00

abstract：:Background: The Maslach Burnout Inventory-Human Services Survey (MBI-HSS) is the most commonly used instrument to assess burnout. Although various factors have been reported to influence its validity, the influence of major depressive disorder (MDD) has not been previously considered. We developed this study to invest...

journal_title：Frontiers in psychiatry

authors： Trigo TR,de Freitas CCS,Wang YP,Ribeiro FG,de Lucia MCS,Siqueira JO,Iosifescu DV,Hallak JEC,Fraguas R

更新日期：2018-12-18 00:00:00

abstract：:Introduction: Recent research in Western countries has indicated that family interventions in schizophrenia and other psychotic disorders can reduce patient relapse and improve medication compliance. Few studies have addressed Chinese and Asian populations. This study tested the long-term effects of a 9-month family-l...

journal_title：Frontiers in psychiatry

authors： Chien WT,Bressington D,Chan SWC

更新日期：2018-12-18 00:00:00

abstract：:The rapidly increasing number of patients with Alzheimer's disease (AD) worldwide has become a major public concern. Mild cognitive impairment (MCI), characterized with accelerated memory decline than normal aging, is a stage between cognitively unimpaired and dementia. Identification of MCI in the Alzheimer's continu...

journal_title：Frontiers in psychiatry

authors： Lin L,Xing G,Han Y

更新日期：2018-12-06 00:00:00

abstract：:Background: In the past 3 decades, there has been an increase in the number of studies assessing exercise as a form of treatment for substance use disorders (SUDs). While a variety of substance types and outcomes have been assessed, exercise intensities have never been systematically examined. Consequently, it remains...

journal_title：Frontiers in psychiatry

authors： Colledge F,Gerber M,Pühse U,Ludyga S

更新日期：2018-12-04 00:00:00

abstract：:Extending beyond the motor domain, the cerebellum is involved in various aspects of cognition and affect. Multidisciplinary evidence has demonstrated topographic organization of higher-order cognitive functions within the cerebellum. We here review recent neuroimaging research that indicates cerebellar contributions t...

journal_title：Frontiers in psychiatry

authors： Depping MS,Schmitgen MM,Kubera KM,Wolf RC

更新日期：2018-11-29 00:00:00

abstract：:Antipsychotic-induced weight gain is one of the most common adverse effects of antipsychotic treatment. However, there are no well-established interventions for the weight gain yet. In this study, we pooled the data from two clinical trials, which were originally examining the efficacy of betahistine and the efficacy ...

journal_title：Frontiers in psychiatry

authors： Kang D,Jing Z,Li R,Hei G,Shao T,Li L,Sun M,Yang Y,Wang Y,Wang X,Long Y,Huang X,Wu R

更新日期：2018-11-27 00:00:00

abstract：:The gut microbiota are known to have a profound influence on both mucosal and systemic immunity and are important for gastrointestinal (GI) function. In addition, new evidence shows that the microbiota significantly influence neurodevelopment and behavior. Immune dysfunction and GI distress are extremely common in ind...

journal_title：Frontiers in psychiatry

authors： Hughes HK,Ashwood P

更新日期：2018-11-26 00:00:00

abstract：:Over half of those diagnosed with post-traumatic stress disorder (PTSD) have comorbid major depressive disorder (MDD), and rates are even higher among military veterans. Transcranial magnetic stimulation (TMS) may be a safe and efficacious treatment for PTSD, both with and without comorbid MDD. Still, the mechanism of...

journal_title：Frontiers in psychiatry

authors： Petrosino NJ,Zandvakili A,Carpenter LL,Philip NS

更新日期：2018-11-20 00:00:00

abstract：:Background: The personality trait neuroticism has been implicated in a poor response to stress, may relate to increased concentrations of cytokines and the development of depression. Inflammatory mechanisms may also be associated with the onset, severity and symptoms of depression. Both are related to poor antidepress...

journal_title：Frontiers in psychiatry

authors： Schmidt FM,Sander C,Minkwitz J,Mergl R,Dalton B,Holdt LM,Teupser D,Hegerl U,Himmerich H

更新日期：2018-11-20 00:00:00

abstract：:Due to advances over the last several decades, many fields of medicine are moving toward a precision medicine approach where treatments are tailored to nuanced patient factors. While in some disciplines these innovations are commonplace leading to unique biomarker-guided experimental medicine trials, there are no such...

journal_title：Frontiers in psychiatry

authors： Joshi YB,Light GA

更新日期：2018-11-19 00:00:00

abstract：:Alcohol use disorder (AUD) is a devastating public health problem in which both genetic and environmental factors play a role. Growing evidence supports that epigenetic regulation is one major mechanism in neuroadaptation that contributes to development of AUD. Meanwhile, epigenetic patterns can be modified by various...

journal_title：Frontiers in psychiatry

authors： Chen J,Hutchison KE,Bryan AD,Filbey FM,Calhoun VD,Claus ED,Lin D,Sui J,Du Y,Liu J

更新日期：2018-11-15 00:00:00

abstract：:Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) often co-occur and share neurocognitive deficits. One such shared impairment is in duration discrimination. However, no studies using functional magnetic resonance imaging (fMRI) have investigated whether these duration discrimination d...

journal_title：Frontiers in psychiatry

authors： Lukito SD,O'Daly OG,Lythgoe DJ,Whitwell S,Debnam A,Murphy CM,Ashwood K,Stoencheva V,Simonoff E,Rubia K

更新日期：2018-11-14 00:00:00

abstract：:Fragile X syndrome (FXS) is caused by the full mutation (>200 CGG repeats) in the Fragile X Mental Retardation 1 (FMR1) gene. It is the most common inherited cause of intellectual disability (ID) and autism. This review focuses on neuropsychiatric disorders frequently experienced by premutation carriers with 55 to 200...

journal_title：Frontiers in psychiatry

authors： Hagerman RJ,Protic D,Rajaratnam A,Salcedo-Arellano MJ,Aydin EY,Schneider A

更新日期：2018-11-13 00:00:00

abstract：:According to the glutamate hypothesis of schizophrenia, the abnormality of glutamate transmission induced by hypofunction of NMDA receptors (NMDARs) is causally associated with the positive and negative symptoms of schizophrenia. However, the underlying mechanisms responsible for the changes in glutamate transmission ...

journal_title：Frontiers in psychiatry

authors： Mei YY,Wu DC,Zhou N

更新日期：2018-11-06 00:00:00

abstract：:Over the past years, there has been a growing interest in the association between lifestyle psychosocial interventions, severe mental illness, and suicide risk. Patients with severe mental disorders have higher mortality rates, poor health states, and higher suicide risk compared to the general population. Lifestyle b...

journal_title：Frontiers in psychiatry

authors： Berardelli I,Corigliano V,Hawkins M,Comparelli A,Erbuto D,Pompili M

更新日期：2018-11-06 00:00:00

abstract：:Japan recently ordered a string of death sentences for offenders with mental illness. Based on the verdicts, we describe cases where one or more psychiatrists conducted psychiatric evaluations for several months and testified in lay judge courts. We compared these cases with those in which the death penalty was avoide...

journal_title：Frontiers in psychiatry

authors： Kashiwagi H,Hirabayashi N

更新日期：2018-11-02 00:00:00

abstract：:Objective: This study aims to understand the impact of negative life experience (NLE) in auditory hallucinations (AHs) and explain the heterogeneity in phenomenology of auditory verbal hallucinations (AVHs). Method: In depth interviews were conducted with 21 individuals (7 males and 14 females) experiencing AHs and ac...

journal_title：Frontiers in psychiatry

authors： Vallath S,Luhrmann T,Bunders J,Ravikant L,Gopikumar V

更新日期：2018-10-30 00:00:00

abstract：:Background: Australia is a high-income country with increasing income inequality. It is unclear whether Australia's well-developed mental healthcare system is making a difference to population mental health and the Federal Government has targeted outcomes accountability in service funding strategies. In high-income co...

journal_title：Frontiers in psychiatry

authors： Isaacs AN,Enticott J,Meadows G,Inder B

更新日期：2018-10-26 00:00:00

abstract：:Disrupted white matter (WM) integrity in the anterior thalamic radiation (ATR) has been identified in individuals with bipolar disorder (BD). We explored whether structural WM aberration in the ATR could be visually evaluated by diffusion tensor tractography (DTT). The study comprised 114 participants, including 57 pa...

journal_title：Frontiers in psychiatry

authors： Niida R,Yamagata B,Niida A,Uechi A,Matsuda H,Mimura M

更新日期：2018-10-24 00:00:00

abstract：:Co-design, defined as collective creativity across the entire design process, can lead to the development of interventions that are more engaging, satisfying, and useful to potential users. However, using this methodology within the research arena requires a shift from traditional practice. Co-design of eHealth interv...

journal_title：Frontiers in psychiatry

authors： Thabrew H,Fleming T,Hetrick S,Merry S

更新日期：2018-10-18 00:00:00

abstract：:Post-stroke depression (PSD) is one of the most frequent complications of stroke. The Yi-nao-jie-yu prescription (YNJYP) is an herbal prescription widely used as a therapeutic agent against PSD in traditional Chinese medicine. Disruption of adult neurogenesis has attracted attention as a potential cause of cognitive p...

journal_title：Frontiers in psychiatry

authors： Tian H,Li X,Tang Q,Zhang W,Li Q,Sun X,Zhao R,Ma C,Liu H,Gao Y,Han F

更新日期：2018-10-16 00:00:00

abstract：:Aims: Expression of inflammatory cytokines in the brain has been reported to be involved in the pathogenesis of and susceptibility to depression. Jumonji domain-containing 3 (Jmjd3), which is a histone H3 lysine 27 (H3K27) demethylase and can regulate microglial activation, has been regarded as a crucial element in th...

journal_title：Frontiers in psychiatry

authors： Wang R,Wang W,Xu J,Liu D,Jiang H,Pan F

更新日期：2018-10-11 00:00:00

abstract：:Background: Bipolar disorder (BD) has been associated with distributed network disruption, but little is known on how different clinical subtypes, particularly those with an earlier and later onset of disease, are related to connectivity changes in white matter (WM) tracts. Methods: Diffusion tensor imaging (DTI) and ...

journal_title：Frontiers in psychiatry

authors： Alves GS,Knöchel C,Paulitsch MA,Reinke B,Carvalho AF,Feddern R,Prvulovic D,Sudo FK,Pantel J,Reif A,Oertel V

更新日期：2018-10-09 00:00:00

abstract：:Background: More information is needed about the efficacy and safety of long-term baclofen in the treatment of alcohol use disorders. The objective of this study was to assess the effect of treatment with tailored-dose baclofen on alcohol consumption in patients with alcohol use disorders followed for 3 years after fi...

journal_title：Frontiers in psychiatry

authors： Pinot J,Rigal L,Granger B,Sidorkiewicz S,Jaury P

更新日期：2018-10-08 00:00:00

abstract：:Introduction: Post-Traumatic Stress Disorder (PTSD) is a prevalent, severe and tenacious psychopathological consequence of traumatic events. Neurobehavioral mechanisms underlying PTSD pathogenesis have been identified, and may serve as risk-resilience factors during the early aftermath of trauma exposure. Longitudinal...

journal_title：Frontiers in psychiatry

authors： Ben-Zion Z,Fine NB,Keynan NJ,Admon R,Green N,Halevi M,Fonzo GA,Achituv M,Merin O,Sharon H,Halpern P,Liberzon I,Etkin A,Hendler T,Shalev AY

更新日期：2018-10-04 00:00:00

abstract：:Alcohol Use Disorder (AUD) is a chronic and relapsing condition characterized by harmful alcohol intake and behavioral-cognitive changes. AUD is the most common cause of liver disease in the Western world. Alcohol abstinence is the cornerstone of therapy in alcoholic patients affected with liver disease. Medical recom...

journal_title：Frontiers in psychiatry

authors： Mosoni C,Dionisi T,Vassallo GA,Mirijello A,Tarli C,Antonelli M,Sestito L,Rando MM,Tosoni A,De Cosmo S,Gasbarrini A,Addolorato G

更新日期：2018-10-01 00:00:00

abstract：:Objective: To evaluate perceived needs and difficulties related to instruments for assessing work ability in individuals with mental disorders. Method: We conducted an online survey of 104 German-speaking medico-legal experts (forensic psychiatric and psychology experts, insurance physicians) and therapists. Results: ...

journal_title：Frontiers in psychiatry

authors： Schleifer R,Gamma A,Warnke I,Jabat M,Rössler W,Liebrenz M

更新日期：2018-09-25 00:00:00

abstract：:Background: Psychiatric comorbidity is common in gambling disorder, a condition with low rates of treatment seeking. There is a paucity of documented nationwide data on gambling disorder and its co-occurring psychiatric comorbidities in the health care system. Methods: This is a nationwide register-based study of all ...

journal_title：Frontiers in psychiatry

authors： Håkansson A,Karlsson A,Widinghoff C

更新日期：2018-09-07 00:00:00

abstract：:Objective: To analyze sex differences in demographic and clinical characteristics of individuals who died by suicide in Mexico City. Method: Statistical analysis of residents of Mexico City whose cause of death was suicide, during two years period from January 2014 to December 2015, with a coroner's report. Suicide mo...

journal_title：Frontiers in psychiatry

authors： Romero-Pimentel AL,Mendoza-Morales RC,Fresan A,Garcia-Dolores F,Gonzalez-Saenz EE,Morales-Marin ME,Nicolini H,Borges G

更新日期：2018-09-07 00:00:00

abstract：:Motivated behaviors are often initiated in response to perturbations of homeostasis. Indeed, animals and humans have fundamental drives to procure (appetitive behaviors) and eventually ingest (consummatory behaviors) substances based on deficits in body fluid (e.g., thirst) and energy balance (e.g., hunger). Consumpti...

journal_title：Frontiers in psychiatry

authors： Hsu TM,McCutcheon JE,Roitman MF

更新日期：2018-09-03 00:00:00

abstract：:Introduction: Previous studies have indicated that changes in the concentration of glutamate and related metabolites may mediate the progression of addiction in patients with methamphetamine (MA) use disorders. In the present study, we utilized magnetic resonance spectroscopy (MRS) to investigate absolute glutamate co...

journal_title：Frontiers in psychiatry

authors： Yang W,Yang R,Luo J,He L,Liu J,Zhang J

更新日期：2018-08-31 00:00:00

abstract：:Cogmed Working Memory Training (CWMT), an online cognitive training program developed for children, is an increasingly popular non-pharmacological intervention for ADHD amongst all ages, despite limited supporting evidence. The initial objective of the present work was to examine the short- and long-term impacts of CW...

journal_title：Frontiers in psychiatry

authors： Marcelle ET,Ho EJ,Kaplan MS,Adler LA,Castellanos FX,Milham MP

更新日期：2018-08-28 00:00:00

abstract：:The aim of this study is to explore the changes and clinical significance of serum C3, C4, hypersensitive C-reactive protein (hsCRP) and uric acid (UA) in patients of bipolar disorder (BD). In this case-control study, we recruited 141 BD patients from The Second Xiangya Hospital, Central South University, and 151 age ...

journal_title：Frontiers in psychiatry

authors： Yang X,Tao H,Xiao L,Li C,Tang Y,Liu Y

更新日期：2018-08-21 00:00:00

abstract：:Hospital midwives and neonatal intensive care (NICU) nurses frequently encounter work-related stressors and are therefore vulnerable to developing mental health problems, such as secondary traumatic stress, burnout, anxiety, and depression. However, so far, the exact nature of these work-related stressors (traumatic v...

journal_title：Frontiers in psychiatry

authors： Favrod C,Jan du Chêne L,Martin Soelch C,Garthus-Niegel S,Tolsa JF,Legault F,Briet V,Horsch A

更新日期：2018-08-20 00:00:00

abstract：:Background: Opiates, cannabis, and stimulants are highly abused and are prevalent disorders. Psychological interventions are crucial given that they help individuals maintain abstinence following a lapse or relapse into substance use. The dual-process theory has posited that while the repeated use of a substance leads...

journal_title：Frontiers in psychiatry

authors： Zhang MWB,Ying J,Wing T,Song G,Fung DSS,Smith HE

更新日期：2018-08-15 00:00:00

abstract：:Sleep-related breathing disorders could be accompanied by or caused by a variety of medical conditions. They are considered to be a significant medical and social problem. Together with excessive daytime sleepiness, patients with obstructive sleep apnea experience neuropsychological symptoms such as anxiety, attention...

journal_title：Frontiers in psychiatry

authors： Bilyukov RG,Nikolov MS,Pencheva VP,Petrova DS,Georgiev OB,Mondeshki TL,Milanova VK

更新日期：2018-08-07 00:00:00

abstract：:Objective: To analyze the predictive value of antepartum vulnerability factors, such as social support, coping, history of psychiatric disease, and fear of childbirth, and intrapartum events on the development of symptoms of postpartum posttraumatic stress disorder (PP-PTSD) in women with a traumatic childbirth experi...

journal_title：Frontiers in psychiatry

authors： van Heumen MA,Hollander MH,van Pampus MG,van Dillen J,Stramrood CAI

更新日期：2018-07-31 00:00:00

abstract：:Background: The clinical and etiological heterogeneity of mood disorders impede identification of effective treatments for the individual patient. This highlights a need for early neuronal and behavioral biomarkers for treatment efficacy, which can provide a basis for more personalized treatments. The present systemat...

journal_title：Frontiers in psychiatry

authors： Seeberg I,Kjaerstad HL,Miskowiak KW

更新日期：2018-07-26 00:00:00